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Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice

Accumulation of ARG1 has been shown to drive polyamine production from the urea cycle (Lou et al., 2020)

Fragment-based lead discovery

Moreover, several hormones were also found to affect 2,3-DPG red cell concentration or oxygen affinity, including cortisol and aldosterone, androgen, growth hormone, thyroid hormone and erythropoietin

Wang S, Chen J, Li P, Chen Y

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