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doi: 10.3389/fmicb.2023.1085818 Received 31 October 2022 Accepted 24 March 2023 Published 14 April 2023 Volume 14 - 2023 Edited by Aibo Wu, Shanghai Institute of Nutrition and Health (CAS), China Reviewed by Carlos Augusto Fernandes Oliveira, University of So Paulo, Brazil

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While normal erythrocytes live 120 days, sickle erythrocytes typically last only 1020 days due to the processes of extravascular phagocytosis and intravascular haemolysis (Crosby, 2007)

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