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One well-documented interaction is with certain anti-epileptic drugs: high-dose pyridoxine may reduce the plasma levels of phenytoin and phenobarbital by enhancing their hepatic metabolism, potentially diminishing their anticonvulsant efficacy

Common side effects of both drugs include nausea, diarrhea, and constipation

Vitamin B12 injections rarely cause digestive issues

Compound AOD-9604 Class Synthetic hGH C-terminal fragment (16 aa) FDA Status Not FDA-approved Evidence Strength Phase 2b primary endpoint missed

Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis