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Results for red blood cell were normalized per protein content in the samples, e.g nmol/mg of protein

These dietary antioxidants help maintain redox balance, modulate immune responses, and improve endothelial and placental function through distinct molecular mechanisms, including Nrf2 activation (vitamin C) [109], NF-B inhibition (vitamin E) [105], AMPK/SIRT1 modulation (polyphenols) [110] and pro-resolving mediator synthesis via GPR120 (omega-3 fatty acids) [108]

Addressing these knowledge gaps through genotype-stratified trials, the inclusion of advanced disease and co-infected cohorts, and transparent TRL mapping will be key to transitioning from promising proof-of-concept to clinically adoptable and affordable therapies [209,210,211]

Extraction A few extraction strategies have been used for solvents extraction utilized for the confinement of particular bio-dynamic mixes ( Aqueous Extraction In aqueous extraction, water is used as an extraction medium due to the polar nature of the molecule and extracts polar compounds like-nucleosides and polysaccharides