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12K), tail DNA percentage (Fig

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30 A major function of the TRIF-dependent TLR signaling pathway is to mediate the induction of Type I IFNs and IFN-inducible genes

Collectively, these results demonstrate that Sororins CTR directly and specifically binds the RAD21-SMC3 interface in a cell-cycle-regulated manner on chromatin, consistent with a model in which Sororin stabilizes cohesion by locking the closed DNA exit gate of cohesin

Nature 591 , 652658 (2021)

Children appear to be especially sensitive, and early-life mold exposure is associated with asthma development or exacerbation in pediatric populations