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In the in vivo experiments, mice were shaved (Back: 2 3 cm [2]) on the 50th day from birth and the depilated areas were coated with saline, 5 % minoxidil, CaT containing 2 % copper peptides, and CaT-ME containing 2 % copper peptides daily after shaving, with 6 mice per group

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Some studies also point to its role in supporting brain-derived neurotrophic factor, a protein that helps neurons survive and form new connections

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The absence of substantial modern follow-up research may reflect limited reproducibility, insufficient clinical benefit, pharmaceutical development challenges, or reduced scientific interest relative to newer sleep therapeutics [1617]