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Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice

L2HG promotes chromatin accessibility through histone hypermethylation for gene regulation

Rogers DF, Alton EW, Dewar A, Lethem MI, Barnes PJ

People who follow a strict vegan diet can also get Vitamin B12 deficiency

Bor MV, Von castel-roberts KM, Kauwell GP, et al

Under physiological conditions, a healthy gut microbiota and an intact intestinal barrier are critical for establishing immune tolerance ( The tumor immune microenvironment (TIME), a dynamic ecosystem of cancer cells, stromal cells, ECM, and diverse immune cells, profoundly shapes tumor progression and therapeutic responses ( A pivotal mechanism linking gut dysbiosis to pro-tumorigenic inflammation is the translocation of microbial components, most notably lipopolysaccharide (LPS), across a compromised intestinal barrier ( Beyond TLR-dependent microbial sensing, the NF-B pathway serves as a critical signaling hub that integrates diverse pro-tumorigenic stimuli within the TIME