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Clinical studies have confirmed that the number of Ki67 + and phosphorylated STAT3 + hepatocytes and cholangiocytes in patients with alcoholic cirrhosis is significantly decreased, indicating that hepatocyte proliferation is inhibited (Horiguchi et al., 2007)

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Cloudiness or precipitation in a clear serum may indicate peptide aggregation from pH shift or temperature damage

In the MMSAVE 2 group, MDA content and chl a and chl b activities decreased by 33.5%, 36.7%, and 35.7%, respectively, compared to the MMS group

In these patients, it is mainly caused by tight junction protein abnormalities, whereas during disease activity, severe mucosal damage disrupts the barrier and causes uncontrolled leakage of the luminal contents [36]

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