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22 Thus, the initiation and development of many inflammatory and immune responses may be physiologically dependent on mast cell-derived cytokines, independently of any allergic reaction (Table 2

Cells possessing this ability of enhanced invasion start to invade surrounding tissue with the support of proteolytic enzymes secreted to degrade the ECM and provide a route of invasion (119)

It is also easy to see and reach, and may feel less invasive than using your abdomen

Better blood vessel growth helps improve circulation

doi: 10.1016/0043-1354(94)90117-1