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Analysis of resource saving showed the switchover of 26.8% ( n = 10) of patients reduced annual nurse consultations by 46

17 Note: Inhalation dosing is typically 600mg/dose in 4-8mL of water

Tominersen in adults with manifest Huntingtons disease

Additionally, 50 healthy elderly subjects received either placebo (n = 20) for 4 weeks or 25 mg of MK-677 (n = 30) daily for 2 weeks followed by 50 mg daily for 2 weeks

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For younger, healthier, lighter individuals, titration runs cautiously pushing past the efficacious dose tends to bring on undesirable side effects