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Barends M, Verschuren L, Morava E, Nesbitt V, Turnbull D, McFarland R (2016) Causes of death in adults with mitochondrial disease

intestinal permeability increases, allowing toxic substances or harmful molecules produced by microorganisms to pass through the intestinal surface and enter systemic circulation

Crepuscular animals can be used in vivo as they are relatively small and easy to keep, and ex vivo tissue is readily available

Although some genes that were typically associated with ISR and cholesterol and FA biosynthesis were also upregulated and downregulated, respectively, in Cse / mice on a no-Trp diet in comparison to Cse +/ and Cse / mice on the control diet, their induction on the no-Cys diet was significantly more pronounced, underscoring a special role of cysteine in the regulation of ISR and fat metabolism (Fig

To view a copy of this licence, visit About this article Cite this article Hu, W., Zhang, J., Wang, H