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Heart failure drugs like Novartiss Entresto (~$6.0 B also rank high

It usually occurs in people with chronic, untreated acid reflux (GERD)

But interesting biology and plausible mechanisms are where drug development begins, not ends

This FDA-approved treatment has been associated with some side effects, which include: a hollowed look to the face, nausea, vomiting, diarrhea, and constipation

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Ongoing investigations assess 5-Amino-1MQs potential applications in obesity-related models, metabolic disease research, insulin sensitivity pathways, and age-associated cellular function studies