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Chen Y, Yang Q, Xu J, Tang L, Zhang Y, Du F, et al

Emphasis is placed on the fundamental translational challenges revealed by GFLs-based clinical trials (such as GDNF and neurturin [NRTN]), including delivery bottlenecks, treatment timing, and limitations of disease models

Recap: GABA is created from glutamate using GAD1 or GAD2 enzymes with vitamin B6 as a cofactor

Failures and successes of NMDA receptor antagonists: Molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults

The drug is then incorporated into the hydrogel, and the gel is injected or implanted into the body