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Furthermore, many mechanisms are shared among diseases and disease subtypes, resulting in the potential for common strategies for BBB repair

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3.6 Multiple sclerosis Multiple sclerosis (MS) is an autoimmune disease characterized by central nervous system (CNS) demyelination, axonal injury, and neurodegeneration as the main pathological changes (216, 217)

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PTEN protein is capable of dephosphorylating both phosphotyrosine and phosphothreonine-containing substrates