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The local oxidative stress created by PDT is antagonized in cells by three primary antioxidant mechanisms: SOD, CAT, and the GSH system [152]

Nikolaou, S

Newly formed aldehyde can spontaneously undergo nucleophilic addition with Lys and hydroxylysine residues in adjacent collagen fibers creating covalent cross-linking [1,2], which enhances structural integrity

ECAR was measured in unbuffered RPMI without phenol red supplemented with glucose (10mM), L- glutamine (2 mM), and sodium pyruvate (1 mM) final concentrations per well

Animal studies demonstrate enhanced angiogenesis and collagen formation in tendon and ligament injuries