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Application of natural products in inducing ferroptosis in tumor cells The active ingredients of natural products originating from the plant kingdom mainly include flavonoids, alkaloids, polysaccharides, volatile oils, quinones, terpenoids, lignans, coumarins, saponins, cardiac glycosides, phenolic acids, amino acids and enzymes

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Microarray and RNA-sequencing studies have mapped its regulatory effect across approximately 4,000 human genes, including upregulation of VEGF, BDNF, and BMP-2 growth factors central to vascular, neural, and bone remodeling respectively