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In summary, our findings offer insights into the neural mechanisms of opioid-induced constipation and help clarify the limited efficacy peripheral opioid receptor antagonists in treating opioid-induced constipation patients

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Free Radic Res 50(2):143149 Seibt TM, Proneth B, Conrad M (2018) Role of GPX4 in ferroptosis and its pharmacological implication

Materials and methods Animals and treatment Thirty Wistar rats were obtained from the Central Animal House of the Faculty of Medicine of Ribeiro Preto, University of So Paulo, after approval by the institution's Ethics Committee of Animal Experimentation

Il jouerait notamment un rle dans les maladies auto-immunes, en limitant lemballement immunitaire caractristique de ces pathologies

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