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If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for Pemetrexed Injection adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity [see Dosage and Administration (2.5), Drug Interactions (7), and Clinical Pharmacology (12.3)]

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The density of the 96-well plate was 5000 cells/well, and the cells were incubated overnight under growth conditions

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The rating reflects recent purity-focused passes, not tight fill consistency