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But as we age, and with increasing exposure to pollutants and stress, our natural glutathione levels decline

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These effects were reduced by the inhibitor L-NAME and tetraethylammonium chloride ( In a study conducted on SHR, the administration of protocatechuic acid, a phenolic compound, enhanced insulin- and insulin-like growth factor-1 (IGF-1)-induced vasorelaxation, indicating improved endothelial responsiveness

On the inflammatory front, curcumin inhibits microglial activation and downregulates the expression of inflammatory enzymes and cytokinesfor instance, it suppresses iNOS and COX-2 induction and lowers levels of TNF- and other interleukins in activated glial cells (72)

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10.3390/cells9040851 Cells 153 SaitouM.Ando-AkatsukaY.ItohM.FuruseM.InazawaJ.FujimotoK.et al (1997)