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We have previously demonstrated that pituispheres genetically correspond to the PitNET tissues, showing that pituispheres might be a valuable novel model system for PitNET tumourigenesis and therapy response studies [21]

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To understand the lack of Pasteur effect in tumors, the following must be born in mind: (i) in cancer cells hexokinase remains active, even in the presence of glucose-6-phosphate (Fig

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ER, endoplasmic reticulum

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