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doi: 10.3390/v15071545 79 StylianouEAukrustPBendtzenKMllerFFrlandSS

[] Another 8-week trial involving 52 benign prostatic hyperplasia (BPH) patients demonstrated that combined supplementation of lycopene and FruHis resulted in a more significant reduction in insulin-like growth factor 1 (IGF-1), total prostate-specific antigen (TPSA), symptom score, body mass index (BMI), and waist circumference (WC) compared with either supplement alone, with a notable effect observed specifically for IGF-1

No substantial protocol amendments affecting eligibility criteria, outcomes, or analyses were made after trial initiation

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