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Again, it causes patients to delay treatment or forego it altogether

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On the other hand, it has been demonstrated that beclin-1 can not only affect the regulation of autophagy as an autophagy regulator, but also affect the intake of cystine by combining with XCT to form the beclin-1/XCT complex, which leads to the inhibition of GPx4 synthesis and the increase of lipid peroxidation level (41)

(Gast et al., 1995)

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