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doi: 10.1208/s12248-017-0098-0 79 ShahPShlanksy-GoldbergRMartinLNadolskiGHexnerEShamimi-NooriSet al

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Metabolite identification was carried out using Chenomx NMR Suite (Chenomx Inc., Edmonton, Canada), supplemented by literature data and confirmed by comparison with chemical shift information from the Human Metabolome Database (HMDB) and the Biological Magnetic Resonance Data Bank (BMRB)

The side effects may vary in all the users and depend on the health condition and response to the therapy

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Reason for escalation: gradual increase allows researchers to assess metabolic response and tolerability