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The mean concentrations of both tGSH and GSSG in the CSF of ALS patients were almost unchanged between the first and the second visits (0.44 0.2 mol/L vs 0.43 0.16 mol/L for tGSH, and 0.18 0.1 mol/L vs 0.18 0.08 mol/L for GSSG)

The mechanism was further explored by adding ferroptosis agonist Erastin

PMID: 17603859

To examine alterations in amino acid profiles associated with hyperuricemia, we conducted targeted amino acid profiling of serum from hyperuricemia Uox-KO mice

Iron worker The study also bolsters the theory that glutathione is a chaperone for iron, which is required for virtually all functions within a cell, Birsoy says