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Because immune dysregulation is a main feature of severe COVID-19 and other inflammatory diseases, it is important to understand how the metabolism of immune cells changes with disease progression

However, even stress can cause free radical damage

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A high level of HLA-I on MM cell membranes may be involved in protecting these cells from NK-mediated attack and contribute to the immune evasion [39]

Other molecules involved in determining vaccine effectiveness include cytokines (interleukins, interferons, chemokines, hematopoietic growth factors, tumor necrosis factors and transforming growth factors), which are small molecular weight proteins that regulate maturation, activation, proliferation and differentiation of the cells of the immune system