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Description

Itaconate, derived from citrate produced in the TCA cycle, contains ,-unsaturated carboxylic acid, and covalently modifies at the Cys151 residue of Keap1 (78)

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Results from these multi-scale approaches reveal that cysteines 8 and 83 are the main targets of glutathionylation and oxidation that lead to loss of activity, while cysteine 79 is less vulnerable to oxidation

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Breen et al

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Therefore, it is referred to as an inorganic arsenic (39)

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M., Heinbockel, M., Dockery, P., Ulmer, H

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3, the PI3K/Akt/mTOR pathway is known to influence iron metabolism and ferritinophagy

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