glutathione metabolic process an damino acid metabolism amino Major metabolic and biosynthetic fates

Some researchers have shown that metformin activates AMPK and triggers the downstream GSH system to slow DOX-mediated oxidative impairment in the myocardium [225, 226]

EC 3.1.3.11), a Mg 2+ -dependent enzyme located in the cytosol

He, L., Zhang, C

Dutta D, Meth B, Amar S, Morris A, Lim SH (2019) Intestinal injury and gut permeability in sickle cell disease

Addressing these multifaceted gaps through integrative, interdisciplinary strategies may unlock the full therapeutic potential of polyphenols in combating AD pathogenesis

So, additional investigation is necessary to link these potential associations to konzo pathogenesis, particularly in relation to time of disease onset, as such markers may only be present during early phases of konzo onset when inflammation or neural damage is likely highest