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For example, in patients with metastatic breast cancer, bevacizumab (Avastin), a humanized anti-VEGF monoclonal antibody, has been found to regulate the vasculature, restore DC maturation, and diminish Tregs [75,78]

Enzyme-like activity of GSH-CDs The superoxide dismutase (SOD)-like activity of the GSH-CDs in removing superoxide anions (O 2 ) was evaluated according to the instructions of the total superoxide dismutase assay kit with nitrogen blue tetrazole (NBT)

Human embryonic stem cell-derived MSCs can also treat CTX-induced POF mice, potentially through paracrine mechanisms that involve the secretion of VEGF, IGF-2, and hepatocyte growth factor which help improve ovarian function, reduce granulosa cell apoptosis, and restore fertility [129]

[DOI] [PubMed] [Google Scholar] 528

In this review, we provide a systematic and comprehensive introduction to immunosenescence at three different levels: molecular, cellular and disease

and Dunn, W., American Journal of Occupational Therapy , 2007, vol