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10.1016/S0021-9258(19)78223-4

While true pharmacological tolerance to GLP-1 receptor agonists is not well-established, tachyphylaxis of the gastric emptying effect has been documented with GLP-1 receptor agonists

Elizabeth N, Natasha J, Matthew G, Kahealani U, Megan S, Karima D, et al

This allows the FTP client program to grab one (usually allocated by the system) and then tell the server to connect using whatever port it happened to grab