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USA 111 , 80198024 (2014)

NAPQI, due to acetaminophen ingestion, binds to and inhibits glutathione synthetase, reducing glutathione production

Involvement of Nrf2, P38, B-Raf, and Nuclear Factor-kappaB, but Not Phosphatidylinositol 3-kinase, in Induction of Hemeoxygenase-1 by Dietary Polyphenols

10 Conclusion and outlook MM, a B-cell-derived malignant clonal proliferation of plasma cells, ranks as the second most prevalent hematologic malignancy, accounting for 15%20% of hematological cancer-related mortality ( While NPs demonstrate potential to modulate ferroptosis through multidimensional mechanisms influencing MM progression, critical challenges hinder clinical translation

Finally, we identify rosmarinic acid (RA) as a potent agonist of PRDX1 with a dissociation constant at nanomolar levels