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Factors influencing recovery: extent of tissue damage age activity level rehabilitation consistency overall health status treatment approach Some individuals may begin noticing improvement within several weeks, while more complex injuries may require longer recovery periods

In some embodiments, concentration of a dye in any otic formulation described herein is less than 2%, less than 1.5%, less than 1%, less than 0.5%, less than 0.25%, less than 0.1%, or less than 100 ppm of the total weight and/or volume of any formulation or composition described herein