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Overcoming Cancer Chemotherapy Resistance by the Induction of Ferroptosis

Although there are many studies on caffeine and EGCG, there are few multilevel horizontal comparisons between the two drugs, as treatments

217 Similarly, PS2 overexpression increases p53 levels and activity to promote p53-dependent cell death, which indicates that APP and its proteolytic products play important roles in the regulation of p53 levels and activity

Figure 2 shows the cytosolic concentration of GSH in our model liver cells for 10 hours after the concentration of the enzyme GCS was set to zero

Moreover, Lan et al

Although ferroptosis does not seem to be programmed, it is tightly controlled in the sense of being enabled or limited, depending on the presence or absence of various promoting or inhibiting factors