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People with a vitamin B12 deficiency are often fatigued and have pale skin

For example, a person may begin to follow a command (lift your leg, squeeze my finger) and then not do so again for a time

If youre experiencing hair loss, your hair follicles aren't actually dead

The reason for this is that the initial wave of drug-induced hepatocellular destruction is followed by a robust innate immune response, in which invading inflammatory cells release toxic oxidants and cause a second wave of destruction

This finding does not establish causality, but it is consistent with a model in which robust mitochondrial peptide signaling is a feature of successful aging rather than a peripheral correlate