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Exon Publications, Australia, pp 6582 Esse R, Barroso M, Tavares de Almeida I, Castro R (2019) The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art

It includes a broad range of vital functions such as storage of material absorbed from the digestive tract, hormone catabolism, synthesis of different compounds like clotting factors, globulin, and albumin and detoxification reactions

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A dense extracellular matrix (ECM),rich in collagen and hyaluronic acid, forms a physical barrier that restricts drug penetration and distribution