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For individuals with digestive sensitivities, those taking acid-reflux medications, or anyone on a plant-based (vegan/vegetarian) diet, absorbing enough B12 through food or pills is virtually impossible

Reference: Sikiric et al., 2010 Nitric oxide system involvement in BPC 157 effects PubMed: 2

Interestingly, direct fibroblast proliferation as measured by cell assay was not significantly affected, suggesting the mechanism is more nuanced than simple cell replication

However, its impact extends beyond glycemic control

Altered GH-IGF-1 axis in severe obese subjects is reversed after bariatric surgery-induced weight loss and related with low-grade chronic inflammation

Growth hormone secretagogues like Ipamorelin enhance the overall regenerative environment by increasing systemic IGF-1 levels