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Glutathione peroxidase 1 (GPx1) is the most abundant version, existing in the cytoplasm of nearly all mammalian tissues, whose preferred substrate is hydrogen peroxide

The glutathione peroxidase (GPx) mimetic activity of the selenides and the spirodiazaselenuranes indicates that the substituents attached to nitrogen atom have significant effect on the activity

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Furthermore, elevation in ELF GSH levels was not arbitrary since the CS induced GSH adaptive response after a 3d exposure period prevented GSH levels from dropping below basal levels

CRediT authorship contribution statement Tianqi Liu: Conceptualization, Data curation, Formal analysis, Investigation, Writing original draft