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BAT, distinguished by its high mitochondrial density and extensive vascularization, dissipates energy by nonshivering thermogenesis, whereas WAT primarily serves as an energy storage depot and secretes a variety of metabolic hormones and cytokines [210]

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It also provides systemic benefits such as strengthening the immune system and increasing energy levels

There's a second, less obvious role that sets selenium apart from a general antioxidant: in maturing sperm, one selenoprotein stops being an enzyme and becomes structural scaffolding

Limitations include limited large-scale human clinical evidence, challenges in extrapolating in-vitro concentrations to in-vivo contexts, stability sensitivities (light, heat, alkaline pH), and variability in supplier purity