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p=0.003) and ISA exerting a more pronounced suppression (76%

pH-responsive polymeric nanoparticles, membrane-fusogenic lipid carriers, and other endosomal escape strategies have been developed to prevent lysosomal degradation and enable cytosolic delivery of therapeutic cargos (Karlsson et al., 2019)

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One area of ongoing debate is whether persistent symptoms reflect ongoing infection, residual tissue injury, immune dysregulation, untreated co-infections, autonomic dysfunction, or a combination of these factors