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We posit that changes in EAAT2 expression may represent an intermediate endophenotype, as the developing astroglialneuron interface is dependent on bidirectional signals leading to the rich intertwined bioenergetic connections between these cells

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The diminished leptin levels invigorate the hypothalamus, subsequently increasing appetite and stimulating food intake behaviors

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Additionally, studies have indicated that Met upregulates GPX4 (Ma et al., 2021), reduces MDA levels, and provides protection against neurological impairments following cerebral ischemia ( The novel chlorane diterpenoid analogue Ajudecunoid C (ADC) is more effective in ferroptosis inhibition