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For example, additional treatment of mild and moderate SLE with metformin reduced clinical flares, body weight and prednisone exposure

doi: 10.3389/fendo.2023.1243999 25 WangJLvSChenGGaoCHeJZhongHet al

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PLC is a form of supplemental carnitine that has been shown to stimulate NO production, boost muscle carnitine, and facilitate the transport of free fatty acids into the mitochondria, where they can be used as fuel.[59] Human studies suggest that PLC may improve various aspects of exercise capacity in individuals with peripheral arterial disease or chronic heart failure,[60],[61] pointing toward its cardiovascular benefits