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Similarly, the Zhigancao Decoction has been shown to alleviate arrhythmias and improve autonomic nervous system stability, while concurrently reducing systemic inflammation (34)

Biological factors include age, hormonal status, nutritional deficiencies (particularly vitamin D, calcium, and protein), smoking, diabetes, and certain medications

Therefore, many proposed mechanisms are subjects of ongoing scientific investigation rather than established clinical findings

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Routine laboratory monitoring typically includes renal function, particularly during dose titration, and periodic assessment of pancreatic enzymes if abdominal symptoms develop

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