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IL-8 can influence other immune cells, such as T cells and monocytes, and affect processes like angiogenesis and wound healing 26

Its main focus on legal sales and prevalence data means that the scale of illicit consumption receives comparatively limited attention, despite available evidence suggesting that around one in ten cigarettes is illicit, that a large proportion of vaping products moves through unregulated channels, and that in some markets illegal nicotine pouches may account for almost all consumption, he said

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