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N -acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial

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Further more, oxidized DNA is more resistant to degradation by cytosolic nucleases (Gehrke et al., 2013), therefore oxidants can promote the accumulation of DNA in the cytosol, and potentiate the activation of the cGAS-STING pathway (Gehrke et al., 2013)

Selective depletion of uropathogenic E

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All mice were fed standard rodent chow (PicoLab 5053, LabDiet) and housed in a specific pathogen-free facility at a controlled temperature of 2223 C on a 12-h lightdark cycle