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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.The potential of silymarin for the treatment of hepatic disorders

Because it contains four distinct compounds, protocol design should account for potential interactions between components

It inhibits the pro-survival Akt and ERK1/2 signaling pathways, thereby reducing proliferation and resistance to apoptosis, while also enhancing p53 stability and transcriptional activity, restoring its tumor-suppressive role and promoting hormonally responsive decidualization, a physiological process whose impairment contributes to EMs implantation and persistence (Yu J