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At each Accutane visit, bloodwork will be performed to assess liver enzyme levels and liver function

JW, GT, RW, JS, and TH wrote the first draft of the manuscript

Radioactivity in lysates was measured by liquid scintillation counting and normalized to the quantity of protein in lysates as determined using the Pierce BCA (bicinchoninic acid) Protein Assay Kit (Thermo Fisher)

Reference: Vestergrd H, Gormsen LC, Rmer K, et al

Regarding AR-V7, its expression was increased in the xentuzumab + enzalutamide group compared with the enzalutamide-only group (Weyer-Czernilofsky et al., 2020)

Hesperidin was studied to determine how they affect mice with OVA1-induced AR