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A possibility is that sodium activation of the immune system and associated produced of these cytokines leads to higher expression of CLDN2, which is associated with higher inflammation in an experimental model of colitis [31]

10.1016/j.ijbiomac.2024.134597 167 ZhaoK.HuZ.ChenX.ChenY.ZhouM.YeX.et al (2024b)

389 PI3K signaling has emerged as a central conduit for LPA-driven proliferation across multiple cancers

Different host-tissue microenvironments select for cancer cells with distinct metastatic traits, which gives rise to organ-specific populations of metastatic cells [14]