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Similarly, despite normal serum T3 levels in D2KO mice, brain T3 levels as well as the expression of certain T3 responsive genes in the brain was reduced

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References Alomer RM, da Silva EML, Chen J, Piekarz KM, McDonald K, Sansam CG, Sansam CL, Rankin S (2017) Esco1 and Esco2 regulate distinct cohesin functions during cell cycle progression