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To overcome these challenges, recent studies have focused on improving the therapeutic efficacy of UA in colon, breast and lung cancers using DDS via nanoparticle encapsulation, polymeric micelles and hydrogels [1082]

The administration of rosiglitazone to upregulate AKT can alleviate the dysfunction of endothelial progenitor cells induced by AGEs (Liang et al

Oral contraceptive steroids as promoters of hepatocarcinogenesis in female Sprague-Dawley rats

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We calculated that blood ET contributed approximately 33%, 24%, and 13% for total lung, spleen and kidney ET respectively, while blood hercynine contributed approximately 19% for lung and spleen, and 13% for kidney (Supplementary Data 2p)

The TP receptor antagonist (SQ29548) inhibits both cyclooxygenase (COX)-2 expression and FLS proliferation, and TP agonist U46619 enhances them