MaP555 NHS (cell-permeable fluorogenic dye) sir Contains an E3 ligase ligand

Contains an E3 ligase ligand with a linker and a function group

CAS Number 220904-83-6 Related CAS Molecular Formula C15H8Br2INO2 Molecular Weight 520

364 SMILES OCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

582 Purity (HPLC) >= 95% Solubility DMSO

CPY dye (short for carbopyronine

MaP555 NHS (cell-permeable fluorogenic dye) sir Contains an E3 ligase ligandMaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The good spectroscopic properties, high cell