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doi: 10.1073/pnas.2003432117 17 LedfordH

Am J Med Sci 343(3):244247

Horvath, S

339, 250257 10.1006/abbi.1996.9831 [DOI] [PubMed] [Google Scholar] Antonelou M

When the fixed black cumin oil was administered through PO or IP routes in mice and rats, the acute toxicity studies revealed LD 50 values of 28.8 ml/kg and 2.06 ml/kg, respectively

Future studies should focus on further evaluating the clinical efficacy of direct NOX inhibition and compare these results with existing therapeutic strategies to more definitively assess the potential of NOX in DCM treatment